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Chloroquine diphosphate salt

Catalog No. C6628 Name Sigma Aldrich
CAS Number 50-63-5 Website http://www.sigmaaldrich.com
M. F. C18H32ClN3O8P2 Telephone 1-800-521-8956
M. W. 515.862502 Fax
Purity ≥98% Email
Storage Chembase ID: 134201

SYNONYMS

Title
氯喹 二磷酸盐
IUPAC name
bis(phosphoric acid); {4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine
IUPAC Traditional name
chloroquine; bis(phosphoric acid)
Synonyms
N4-(7-氯-4-喹啉基)-N1,N1-二甲基-1,4-戊二胺 二磷酸盐

DATABASE IDS

PubChem SID 24278090
EC Number 200-055-2
MDL Number MFCD00069852
Beilstein Number 4223142
CAS Number 50-63-5

PROPERTIES

Impurities ≤2% water
Purity ≥98%
Gene Information human ... ABCC1(4363)
Apperance solid
Melting Point 200 °C (dec.)(lit.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Risk Statements 22
RTECS VB2450000
Safety Statements 22-24/25
German water hazard class 3

DETAILS

Description (简体中文)
Application
DNA intercalator. Also used to increase transfection efficiency.
Biochem/physiol Actions
Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).
包装
25, 50, 100, 250 g in glass bottle

REFERENCES