Phorbol 12,13-diacetate

• Catalog No.: P9143
• CAS Number: 24928-15-2
• M. F.: C24H32O8
• M. W.: 448.50608

SYNONYMS

• IUPAC name: (1S,2S,6R,10S,11R,13S,14R,15R)-14-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-13-yl acetate
• IUPAC Traditional name: (1S,2S,6R,10S,11R,13S,14R,15R)-14-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-13-yl acetate
• Synonyms: PDA

DATABASE IDS

• Beilstein Number: 2317312
• PubChem SID: 24899011
• MDL Number: MFCD00036735
• CAS Number: 24928-15-2

PROPERTIES

• Apperance: white powder
• Solubility: H2O: soluble
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H315-H319-H330-H335
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 26/27/28-36/37/38
• RTECS: GZ0651000
• Safety Statements: 26-27-36/37/39-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Activates protein kinase C.
Caution
Photosensitive.
General description
Phorbol ester with enhanced hydrophilicity.
Other Notes
Less potent but more water soluble than phorbol 12,13-dibutyrate.
Reconstitution
Although having aqueous solubility, it is recommended that this compound first be dissolved in a water miscible organic solvent before dilution to working concentrations in aqueous media.