α-Cyano-4-hydroxycinnamic acid

• Catalog No.: C2020
• CAS Number: 28166-41-8
• M. F.: C10H7NO3
• M. W.: 189.16748
• Purity: ≥98% (TLC)

SYNONYMS

• Title: α-氰基-4-羟基肉桂酸
• IUPAC name: (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid
• IUPAC Traditional name: α-cyano-4-hydroxycinnamic acid
• Synonyms: α-CHCA; α-CCA; 4-HCCA; ACCA; α-氰基

DATABASE IDS

• EC Number: 248-879-1
• PubChem SID: 24892459
• CAS Number: 28166-41-8
• MDL Number: MFCD00004204
• Beilstein Number: 3271427

PROPERTIES

• Purity: ≥98% (TLC)
• Apperance: yellow powder
• Melting Point: 245-250 °C(lit.)
• Solubility: H2O: slightly soluble
• Solubility: methanol: water: soluble
• Solubility: polar organic solvents: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
Specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport.1,2,3 Also reported to block β-cell apical anion exchange (IC50 of 2.4 mM).4
包装
10, 25 g in poly bottle
Application
Useful hydrophobic matrix solution for matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Antibiotics, peptide nucleic acids (a new class of DNA mimics), and proteins with masses as high as 66,000 Da have been successfully analyzed by using this as a matrix solution.