α-Nicotinamide adenine dinucleotide, reduced disodium salt

• Catalog No.: N6879
• CAS Number: 108321-31-9
• M. F.: C21H27N7Na2O14P2
• M. W.: 709.404642
• Purity: ≥90%

SYNONYMS

• IUPAC name: disodium [(2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl ({[(2R,3S,4R,5S)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
• IUPAC Traditional name: disodium [(2S,3R,4S,5S)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl {[(2R,3S,4R,5S)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxyphosphonate
• Synonyms: α-NADH; α-Dihydrodiphosphopyridine nucleotide; α-Dihydronicotinamide adenine dinucleotide; α-DPNH

DATABASE IDS

• CAS Number: 108321-31-9
• MDL Number: MFCD00079521
• PubChem SID: 24897797

PROPERTIES

• Impurities: ≤3% β-isomer
• Purity: ≥90%
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Caution
This is not the common NADH required in the usual enzyme systems.
Other Notes
Analog of β-NADH, chemically reduced
Application
α-Nicotinamide adenine dinucleotide, reduced (α-NADH) may be used as a cosubstrate to assess the specificity and kinetics of NAD+/NADH and NADP+/NADPH dependent enzymes and to assess the dynamics of nucleotides in ion channels such as voltage-dependent mitochondrial ion channels (VDAC).