Ampicillin

• Catalog No.: A9393
• CAS Number: 69-53-4
• M. F.: C16H19N3O4S
• M. W.: 349.40476
• Purity: 96.0-100.5% (anhydrous basis)

SYNONYMS

• Title: 氨苄西林
• IUPAC name: (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• IUPAC Traditional name: ampicillin
• Synonyms: 氨苄青霉素

DATABASE IDS

• MDL Number: MFCD00005175
• Beilstein Number: 1090925
• PubChem SID: 24891442
• EC Number: 200-709-7
• CAS Number: 69-53-4

PROPERTIES

• Purity: 96.0-100.5% (anhydrous basis)
• Suitability: suitable for 1694 per US EPA
• Melting Point: 208 °C (dec.)(lit.)
• Solubility: 1 M NH4OH: soluble50 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H317-H319-H334-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P342 + P311
• Risk Statements: 36/37/38-42/43
• RTECS: XH8350000
• Safety Statements: 22-26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Application
Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid 1,2,3,4.