Penicillin G sodium salt

• Catalog No.: PENNA
• CAS Number: 69-57-8
• M. F.: C16H17N2NaO4S
• M. W.: 356.37195

SYNONYMS

• Title: Penicillin G sodium salt 钠盐
• IUPAC name: sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• IUPAC Traditional name: sodium benzylpenicillin(1-)
• Synonyms: Benzylpenicillin sodium salt 钠盐

DATABASE IDS

• PubChem SID: 24899068
• Beilstein Number: 3834217
• CAS Number: 69-57-8
• MDL Number: MFCD00069666
• EC Number: 200-710-2

PROPERTIES

• GHS Signal Word: Danger
• GHS Hazard statements: H317-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P342 + P311
• Risk Statements: 42/43
• RTECS: XH9800000
• Safety Statements: 22-36/37-45
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria.
Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs), which inhibits peptidoglycan chain cross-linking. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.
Application
Penicillin G is narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility 1. It is used in cell culture alone as well as in combination with streptomcyin and other antibiotics2.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information