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Diethylstilbestrol

Catalog No. D4628 Name Sigma Aldrich
CAS Number 56-53-1 Website http://www.sigmaaldrich.com
M. F. C18H20O2 Telephone 1-800-521-8956
M. W. 268.3502 Fax
Purity ≥99% (HPLC) Email
Storage Chembase ID: 140

SYNONYMS

Title
己烯雌酚
IUPAC name
4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
IUPAC Traditional name
estrogen
Synonyms
DES
乙芪酚
(E)-3,4-双(4-羟苯基)3-亚己基

DATABASE IDS

MDL Number MFCD00002373
Beilstein Number 2056095
CAS Number 56-53-1
EC Number 200-278-5
PubChem SID 24893887

PROPERTIES

Purity ≥99% (HPLC)
Gene Information human ... ESR1(2099), ESR2(2100), ESRRG(2104)mouse ... Esr1(13982)rat ... Ar(24208), Esr1(24890)
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Pictograms GHS09
GHS Signal Word Danger
GHS Hazard statements H315-H319-H335-H350-H360-H410
European Hazard Symbols Toxic Toxic (T)
European Hazard Symbols Nature polluting Nature polluting (N)
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P261-P273-P305 + P351 + P338-P308 + P313-P501
RID/ADR UN 3077 9/PG 3
Risk Statements 45-61-36/37/38-51/53
RTECS WJ5600000
Safety Statements 53-36/37/39-45-60-61
Hazard Class 9
UN Number 3077
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone.

REFERENCES