Diethylstilbestrol

• Catalog No.: D4628
• CAS Number: 56-53-1
• M. F.: C18H20O2
• M. W.: 268.3502
• Purity: ≥99% (HPLC)

SYNONYMS

• Title: 己烯雌酚
• IUPAC name: 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
• IUPAC Traditional name: estrogen
• Synonyms: DES; 乙芪酚; (E)-3,4-双(4-羟苯基)3-亚己基

DATABASE IDS

• MDL Number: MFCD00002373
• Beilstein Number: 2056095
• CAS Number: 56-53-1
• EC Number: 200-278-5
• PubChem SID: 24893887

PROPERTIES

• Purity: ≥99% (HPLC)
• Gene Information: human ... ESR1(2099), ESR2(2100), ESRRG(2104)mouse ... Esr1(13982)rat ... Ar(24208), Esr1(24890)
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H319-H335-H350-H360-H410
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P261-P273-P305 + P351 + P338-P308 + P313-P501
• RID/ADR: UN 3077 9/PG 3
• Risk Statements: 45-61-36/37/38-51/53
• RTECS: WJ5600000
• Safety Statements: 53-36/37/39-45-60-61
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone.