Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate

• Catalog No.: A6885
• CAS Number: 37839-81-9
• M. F.: C10H11N5NaO6P
• M. W.: 351.187771
• Purity: ≥98.0% (HPLC)

SYNONYMS

• Title: 腺苷-3′,5′-环单磷酸 钠盐 一水合物
• IUPAC name: sodium (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• IUPAC Traditional name: sodium 3',5'-cyclic amp anion
• Synonyms: 环化腺苷酸 钠盐; cAMP-Na

DATABASE IDS

• PubChem SID: 24891151
• Beilstein Number: 54612
• MDL Number: MFCD00069736
• CAS Number: 37839-81-9

PROPERTIES

• Purity: ≥98.0% (HPLC)
• Apperance: white powder
• Solubility: H2O: soluble50 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (English)

Application
Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.
Biochem/physiol Actions
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.