4α-Phorbol 12,13-didecanoate

• Catalog No.: P8014
• CAS Number: 27536-56-7
• M. F.: C40H64O8
• M. W.: 672.93136

SYNONYMS

• IUPAC name: (1S,2S,6S,10S,11R,13S,14R,15R)-14-(decanoyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-13-yl decanoate
• IUPAC Traditional name: (1S,2S,6S,10S,11R,13S,14R,15R)-14-(decanoyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-13-yl decanoate
• Synonyms: 4αPDD; 4α-Phorbol 12-13-dicaprinate

DATABASE IDS

• MDL Number: MFCD00036737
• Beilstein Number: 2514324
• PubChem SID: 24898900
• CAS Number: 27536-56-7

PROPERTIES

• Apperance: white solid
• Solubility: DMSO: soluble
• Solubility: ethanol: soluble
• Solubility: methanol: soluble
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H330-H334-H351
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 26/27/28-40-43
• Safety Statements: 36/37/39-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Phorbol that is not biologically active, can be used as a negative control.
Biochem/physiol Actions
Skin tumor promoter in experimental animal model.1
Caution
Photosensitive
Reconstitution
Stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.