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L-Cycloserine

Catalog No. C1159 Name Sigma Aldrich
CAS Number 339-72-0 Website http://www.sigmaaldrich.com
M. F. C3H6N2O2 Telephone 1-800-521-8956
M. W. 102.09194 Fax
Purity Email
Storage Chembase ID: 105470

SYNONYMS

Title
环丝氨酸
IUPAC name
(4S)-4-amino-1,2-oxazolidin-3-one
IUPAC Traditional name
(+)-cycloserine
Synonyms
(S)-4-Amino-3-isoxazolidone

DATABASE IDS

EC Number 206-427-0
PubChem SID 24278296
CAS Number 339-72-0
Beilstein Number 80799
MDL Number MFCD00064324

PROPERTIES

Solubility H2O: soluble50 mg/mg protein
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS NY2976000
Storage Temperature -20°C
German water hazard class 2

DETAILS

Description (简体中文)
包装
10, 25, 100 mg in poly bottle
250 mg in poly tube
Biochem/physiol Actions
Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.1
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.

REFERENCES