Erythromycin

• Catalog No.: E5389
• CAS Number: 114-07-8
• M. F.: C37H67NO13
• M. W.: 733.92678

SYNONYMS

• Title: 红霉素
• IUPAC name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• IUPAC Traditional name: erythromycin
• Synonyms: E-Mycin; Erythrocin

DATABASE IDS

• CAS Number: 114-07-8
• EC Number: 204-040-1
• MDL Number: MFCD00084654
• PubChem SID: 24894612
• Beilstein Number: 75279

PROPERTIES

• Impurities: ≤0.1 EU/mg endotoxin
• Potency: ≥850 μg per mg
• Suitability: suitable for cell culture
• Gene Information: human ... ABCB1(5243), CYP3A4(1576), MLNR(2862)mouse ... Abcb1a(18671), Abcb1b(18669)
• Apperance: powder
• Solubility: 2 M HCl: soluble50 mg/mL (Stock solutions should be stored at 2-8 °C. Stable at 37 °C for 3 days.)
• Solubility: ethanol: soluble (Stock solutions should be stored at 2-8 °C. Stable at 37 °C for 3 days.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: KF437500
• German water hazard class: 3

DETAILS

Description (English)

Application
Recommended for use in cell culture applications at 100 mg/L
Biochem/physiol Actions
Inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information