Progesterone

• Catalog No.: P6149
• CAS Number: 57-83-0
• M. F.: C21H30O2
• M. W.: 314.4617

SYNONYMS

• Title: 孕酮
• IUPAC name: (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: progesterone
• Synonyms: 孕烯二酮

DATABASE IDS

• PubChem SID: 24898649
• MDL Number: MFCD00003658
• CAS Number: 57-83-0
• EC Number: 200-350-6
• Beilstein Number: 1915950

PROPERTIES

• Description: synthesized from materials derived from plant source
• Potency: 0.1-20 ng/mL
• Sterility: γ-irradiated
• Suitability: suitable for cell culture
• Gene Information: human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)mouse ... Esr1(13982)rat ... Ar(24208), Nr3c1(24413), Pgr(25154)
• Apperance: powder
• Melting Point: 128-132 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H351
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P281
• Risk Statements: 40
• RTECS: TW0175000
• Safety Statements: 36/37
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
用于细胞培养，研究细胞信号传导和基因表达的甾醇调控。
Other Notes
由卵巢黄体产生的类固醇激素。
Reconstitution
要制备 20μg/mL 的储存液，可加入 1mL 无水乙醇，温和搅拌使之溶解，再加入 49mL 无菌培养基。
Physical form
室温下为粉末状；分成小份冻存，以避免使用时反复冷冻/解冻
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。