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Rifampicin

Catalog No. R7382 Name Sigma Aldrich
CAS Number 13292-46-1 Website http://www.sigmaaldrich.com
M. F. C43H58N4O12 Telephone 1-800-521-8956
M. W. 822.94022 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 134128

SYNONYMS

Title
利福平
IUPAC name
(7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-N-(4-methylpiperazin-1-yl)carboximidoyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
IUPAC Traditional name
(7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-N-(4-methylpiperazin-1-yl)carboximidoyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
Synonyms
利米定
甲哌利福霉素
3-(4-甲基-1-哌嗪基亚胺甲基)利福霉素SV

DATABASE IDS

EC Number 236-312-0
CAS Number 13292-46-1
Beilstein Number 5723476
MDL Number MFCD00151389
PubChem SID 24899391

PROPERTIES

Purity ≥97% (HPLC)
Suitability plant cell culture tested
Apperance crystalline
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H315-H319-H335
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 22-36/37/38
RTECS VJ7000000
Safety Statements 26-36
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Inhibits the assembly of DNA and protein into mature virus particles.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.
Application
Rifampicin, a rifamycin, is active against mycobacteria. Rifamycin, is also an inhibitor of chloroplast RNA polymerase and may be used to study chloroplast-level DNA transcription in plants.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

REFERENCES