Fenoldopam monohydrobromide

• Catalog No.: F6800
• CAS Number: 67287-54-1
• M. F.: C16H17BrClNO3
• M. W.: 386.66808
• Purity: ≥98%
• Storage: protect from light

SYNONYMS

• IUPAC name: 6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide
• IUPAC Traditional name: fenoldopam hydrobromide
• Synonyms: SKF-82526; 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol monohydrobromide

DATABASE IDS

• EC Number: 266-634-7
• CAS Number: 67287-54-1
• PubChem SID: 24278441

PROPERTIES

• Purity: ≥98%
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), DRD1(1812)
• Apperance: off-white
• Solubility: DMSO: >12 mg/mL
• Solubility: H2O: soluble4.75 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H317-H319-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P342 + P311
• Risk Statements: 22-36-42/43
• Safety Statements: 22-26-36/37/39
• Storage Condition: protect from light
• Storage Condition: under inert gas
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Fenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.