Chlorpromazine hydrochloride

• Catalog No.: C8138
• CAS Number: 69-09-0
• M. F.: C17H20Cl2N2S
• M. W.: 355.3251
• Purity: ≥98% (TLC)

SYNONYMS

• Title: 氯丙嗪 盐酸盐
• IUPAC name: [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride
• IUPAC Traditional name: chlorpromazine hydrochloride
• Synonyms: 氯普马嗪; 2-氯-10-(3-二甲氨基丙基)吩噻嗪 盐酸盐; CPZ

DATABASE IDS

• Beilstein Number: 3779989
• EC Number: 200-701-3
• MDL Number: MFCD00012654
• PubChem SID: 24277891
• CAS Number: 69-09-0

PROPERTIES

• Purity: ≥98% (TLC)
• Gene Information: human ... DRD2(1813), HRH1(3269)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H330
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P284-P301 + P310-P310
• RID/ADR: UN 2811 6.1/PG 1
• Risk Statements: 25-26
• RTECS: SO1750000
• Safety Statements: 28-36/37-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
在血红蛋白和过氧化物酶的微量测定中替代联苯胺、邻联茴香胺和邻联甲苯胺。
Biochem/physiol Actions
吩噻嗪类抗精神病药;D2 多巴胺受体拮抗剂，H1 组胺受体拮抗剂;抑制钙调蛋白依赖性环核苷酸磷酸二酯酶和一氧化氮合成酶的活化。
氯丙嗪表现出对白血病细胞的细胞毒性和抗增殖活性，但是不会影响正常淋巴细胞的活力。