Ritanserin

• Catalog No.: R103
• CAS Number: 87051-43-2
• M. F.: C27H25F2N3OS
• M. W.: 477.5687064

SYNONYMS

• IUPAC name: 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
• IUPAC Traditional name: ritanserin
• Synonyms: 6-[2-[4-(bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

DATABASE IDS

• MDL Number: MFCD00069341
• CAS Number: 87051-43-2
• PubChem SID: 24278117

PROPERTIES

• Gene Information: human ... HTR2A(3356)rat ... Adra1a(29412), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr7(65032)
• Apperance: white powder
• Solubility: methanol: >10 mg/mL
• Solubility: DMSO: >10.1 mg/mL
• Solubility: 2-hydroxypropyl-β-cyclodextrin: insoluble
• Solubility: H2O: insoluble
• Solubility: dilute aqueous base: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 22-26-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Potent 5-HT2A serotonin receptor antagonist/inverse agonist that crosses the blood-brain barrier.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R103.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.