Adenosine 5′-O-thiomonophosphate dilithium salt

• Catalog No.: A1640
• CAS Number: 93839-85-1
• M. F.: C10H12Li2N5O6PS
• M. W.: 375.152941
• Purity: ≥98%

SYNONYMS

• IUPAC name: lithium(1+) ion [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (lithiosulfanyl)phosphonate
• IUPAC Traditional name: lithium(1+) ion [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl lithiosulfanylphosphonate
• Synonyms: 5′-AMPS

DATABASE IDS

• CAS Number: 93839-85-1
• MDL Number: MFCD00042996
• PubChem SID: 24890572

PROPERTIES

• Impurities: ≤5 mol/mol water
• Purity: ≥98%
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H371
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P260
• Risk Statements: 20/21/22-68/20/21/22
• Safety Statements: 36/37
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Adenosine 5′′-O-thiomonophosphate (5′-AMPS) is a 5′-O-thiophosphate which along with adenosine 5′-O-(2-thiodiphosphate) and adenosine 5′-O-(3-thiotriphosphate) can act as inhibitors of phosphohydrolases. AMPS is a substrate for smooth muscle endothelial ecto-5′-nucleotidase. 5′APMS is a stimulator of 5-lipoxygenase activity of rat polymorphonuclear (PMN) leukocytes. Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5′-O-phosphorothioates such as 5′-AMPS to nucleoside 5′-O-phosphates.