Spiramycin

• Catalog No.: S9132
• CAS Number: 8025-81-8
• M. F.: C43H74N2O14
• M. W.: 843.05266

SYNONYMS

• Title: 螺旋霉素
• IUPAC name: 2-[(4R,5S,6S,7R,9R,10R,11Z,13Z,16R)-6-({5-[(4,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl}oxy)-10-{[5-(dimethylamino)-6-methyloxan-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
• IUPAC Traditional name: 2-[(4R,5S,6S,7R,9R,10R,11Z,13Z,16R)-6-({5-[(4,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl}oxy)-10-{[5-(dimethylamino)-6-methyloxan-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
• Synonyms: Formacidine

DATABASE IDS

• CAS Number: 8025-81-8
• PubChem SID: 24899826
• EC Number: 232-429-6
• MDL Number: MFCD01314545

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: WG9400000
• Storage Temperature: 2-8°C
• German water hazard class: 1

DETAILS

Description (English)

Quality
A mixture of Spiramycin I, II and III.
Application
Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults 1 and has been used to study septicemia in mice 2.
Biochem/physiol Actions
Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.