Trazodone hydrochloride

• Catalog No.: T6154
• CAS Number: 25332-39-2
• M. F.: C19H23Cl2N5O
• M. W.: 408.32482
• Purity: ≥99% (HPLC)

SYNONYMS

• IUPAC name: 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride
• IUPAC Traditional name: trazodone hydrochloride
• Synonyms: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

DATABASE IDS

• PubChem SID: 24278136
• MDL Number: MFCD00079603
• EC Number: 246-855-5
• CAS Number: 25332-39-2

PROPERTIES

• Purity: ≥99% (HPLC)
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2C(3358)
• Apperance: light yellow powder
• Solubility: methanol: soluble25 mg/mL
• Solubility: 0.1 M HCl: soluble7.4 mg/mL
• Solubility: DMSO: soluble
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H351
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P281
• Risk Statements: 22-40
• RTECS: XZ5660000
• Safety Statements: 22-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Antidepressant that potentiates the activity of serotonin uptake blockers and has full 5-HT2C serotonin receptor agonist activity. It is metabolized to the 5-HT1 serotonin receptor agonist 1-(3-Chlorophenyl)piperazine.