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Trazodone hydrochloride_Molecular_structure_CAS_25332-39-2)
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Trazodone hydrochloride

Catalog No. T6154 Name Sigma Aldrich
CAS Number 25332-39-2 Website http://www.sigmaaldrich.com
M. F. C19H23Cl2N5O Telephone 1-800-521-8956
M. W. 408.32482 Fax
Purity ≥99% (HPLC) Email
Storage Chembase ID: 73240

SYNONYMS

IUPAC name
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride
IUPAC Traditional name
trazodone hydrochloride
Synonyms
2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

DATABASE IDS

PubChem SID 24278136
MDL Number MFCD00079603
EC Number 246-855-5
CAS Number 25332-39-2

PROPERTIES

Purity ≥99% (HPLC)
Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2C(3358)
Apperance light yellow powder
Solubility methanol: soluble25 mg/mL
Solubility 0.1 M HCl: soluble7.4 mg/mL
Solubility DMSO: soluble
Solubility H2O: insoluble
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Warning
GHS Hazard statements H302-H351
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P281
Risk Statements 22-40
RTECS XZ5660000
Safety Statements 22-36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Antidepressant that potentiates the activity of serotonin uptake blockers and has full 5-HT2C serotonin receptor agonist activity. It is metabolized to the 5-HT1 serotonin receptor agonist 1-(3-Chlorophenyl)piperazine.

REFERENCES