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Cortistatin-14

Catalog No. C5808 Name Sigma Aldrich
CAS Number 186901-48-4 Website http://www.sigmaaldrich.com
M. F. C81H113N19O19S2 Telephone 1-800-521-8956
M. W. 1721.00982 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 133967

SYNONYMS

IUPAC name
(2S)-6-amino-2-{[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-13,25,28-tribenzyl-31-(carbamoylmethyl)-16-[(1R)-1-hydroxyethyl]-7,10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-37-[(2S)-pyrrolidine-2-amido]-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-4-yl]formamido}hexanoic acid
IUPAC Traditional name
(2S)-6-amino-2-{[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-13,25,28-tribenzyl-31-(carbamoylmethyl)-16-[(1R)-1-hydroxyethyl]-7,10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-37-[(2S)-pyrrolidine-2-amido]-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-4-yl]formamido}hexanoic acid
Synonyms
CST-14
Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys [Disulfide bridge: 2–13]

DATABASE IDS

CAS Number 186901-48-4
MDL Number MFCD01075120

PROPERTIES

Packaging vial of 0.5 mg
Purity ≥97% (HPLC)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Somatostatin-like neuropeptide with neuronal depressant and sleep modulating properties. Exogenous cortistatin impairs short-term memory processing.1

REFERENCES