Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate

• Catalog No.: A165
• CAS Number: 151837-09-1(anhydrous)
• M. F.: C16H27N6O5PS
• M. W.: 446.461541
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinine-2-thione; triethylamine
• IUPAC Traditional name: (4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2,7-dihydroxy-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinine-2-thione; triethylamine
• Synonyms: Rp-cAMPS triethylammonium salt hydrate; Rp-Cyclic 3′,5′-hydrogen phosphorothioate adenosine triethylammonium salt

DATABASE IDS

• MDL Number: MFCD03703495
• CAS Number: 151837-09-1(anhydrous)
• PubChem SID: 24890575

PROPERTIES

• Purity: ≥98% (HPLC)
• Absorption Wavelength: λmax 258 nm
• Apperance: white solid
• Solubility: H2O: soluble10 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Condition: desiccated
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Rp-Diastereomer of adenosine-3′,5′-cyclic monophosphothioate. Specific membrane-permeable inhibitor of activation by cAMP of cAMP-dependent protein kinase I and II; resistant toward cyclic nucleotide phosphodiesterases; blocks cAMP-mediated effects in numerous systems.
Caution
Extremely hygroscopic. Store desiccated.