Adenosine 2′:3′-cyclic monophosphate sodium salt

• Catalog No.: A9376
• CAS Number: 37063-35-7
• M. F.: C10H12N5NaO6P
• M. W.: 352.195711
• Purity: ≥97%

SYNONYMS

• Title: 腺苷 2′:3′-循环磷酸钠盐 钠盐
• IUPAC name: 4-(6-amino-9H-purin-9-yl)-2-hydroxy-6-(hydroxymethyl)-tetrahydro-2H-1,3,5,2λ^5-furo[3,4-d][1,3,2λ^5]dioxaphosphol-2-one sodium
• IUPAC Traditional name: 4-(6-aminopurin-9-yl)-2-hydroxy-6-(hydroxymethyl)-tetrahydro-1,3,5,2λ^5-furo[3,4-d][1,3,2λ^5]dioxaphosphol-2-one sodium
• Synonyms: 2′,3′-cAMP sodium salt

DATABASE IDS

• CAS Number: 37063-35-7
• EC Number: 253-328-3
• MDL Number: MFCD00005757
• PubChem SID: 24891439

PROPERTIES

• Purity: ≥97%
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Caution
Caution: Do not confuse with the common adenosine 2′(3′)-monophosphate (mixed isomers).
Application
Adenosine 2′,3′-cyclic monophosphate (2′,3′-cAMP) is believed to serve as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.