8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt

• Catalog No.: C240
• CAS Number: 276696-61-8
• M. F.: C22H30ClN6O6PS2
• M. W.: 605.066961
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-sulfanylidene-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-6-yl]-2-amino-8-[(4-chlorophenyl)sulfanyl]-6,9-dihydro-1H-purin-6-one; triethylamine
• IUPAC Traditional name: 9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-sulfanylidene-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-6-yl]-2-amino-8-[(4-chlorophenyl)sulfanyl]-1H-purin-6-one; triethylamine
• Synonyms: Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt; Rp-8-CPT-cGMPS; Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt

DATABASE IDS

• CAS Number: 276696-61-8
• MDL Number: MFCD04037247

PROPERTIES

• Purity: ≥98% (HPLC)
• Apperance: white solid
• Solubility: H2O: soluble5 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Rp-8-CPT-cGMP is a potent inhibitor of protein kinase G Ia, Ib, and type II.
Linkage
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt is more cell permeable than Rp-cGMPS triethylamine.