Aristolochic acid I sodium salt

• Catalog No.: A9451
• CAS Number: 10190-99-5
• M. F.: C17H10NNaO7
• M. W.: 363.25357
• Purity: ≥97%

SYNONYMS

• IUPAC name: sodium 6-methoxy-9-nitro-14,16-dioxatetracyclo[8.7.0.0^2,^7.0^1^3,^1^7]heptadeca-1(10),2(7),3,5,8,11,13(17)-heptaene-11-carboxylate
• IUPAC Traditional name: sodium 6-methoxy-9-nitro-14,16-dioxatetracyclo[8.7.0.0^2,^7.0^1^3,^1^7]heptadeca-1(10),2(7),3,5,8,11,13(17)-heptaene-11-carboxylate
• Synonyms: Aristolochic acid sodium salt

DATABASE IDS

• PubChem SID: 24891454
• MDL Number: MFCD00210760
• CAS Number: 10190-99-5
• EC Number: 233-463-4

PROPERTIES

• Purity: ≥97%
• Apperance: orange-brown powder
• Solubility: H2O: soluble50 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H311-H331-H351
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P280-P301 + P310-P311
• RID/ADR: UN 1544 6.1/PG 3
• Risk Statements: 23/24/25-40
• RTECS: SF8281000
• Safety Statements: 22-36/37/39-45
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Component of some Chinese herbal medicines, and responsible for their nephrotoxicity. Prodrug activated by reduction of the nitro group to an amine, which forms cytotoxic DNA adducts.1