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Amyloid β-Protein Fragment 22-35_Molecular_structure_CAS_144189-71-9)
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Amyloid β-Protein Fragment 22-35

Catalog No. A5080 Name Sigma Aldrich
CAS Number 144189-71-9 Website http://www.sigmaaldrich.com
M. F. C59H102N16O21S Telephone 1-800-521-8956
M. W. 1403.60078 Fax
Purity ≥95% (HPLC) Email
Storage Chembase ID: 133839

SYNONYMS

IUPAC name
4-amino-4-{[1-({1-[({[1-({1-[(5-amino-1-{[({1-[(1-{[1-({[(1-{[1-carboxy-3-(methylsulfanyl)propyl]carbamoyl}-3-methylbutyl)carbamoyl]methyl}carbamoyl)-2-methylbutyl]carbamoyl}-2-methylbutyl)carbamoyl]ethyl}carbamoyl)methyl]carbamoyl}pentyl)carbamoyl]-2-carbamoylethyl}carbamoyl)-2-hydroxyethyl]carbamoyl}methyl)carbamoyl]-2-methylpropyl}carbamoyl)-2-carboxyethyl]carbamoyl}butanoic acid
IUPAC Traditional name
4-amino-4-{[1-({1-[({[1-({1-[(5-amino-1-{[({1-[(1-{[1-({[(1-{[1-carboxy-3-(methylsulfanyl)propyl]carbamoyl}-3-methylbutyl)carbamoyl]methyl}carbamoyl)-2-methylbutyl]carbamoyl}-2-methylbutyl)carbamoyl]ethyl}carbamoyl)methyl]carbamoyl}pentyl)carbamoyl]-2-carbamoylethyl}carbamoyl)-2-hydroxyethyl]carbamoyl}methyl)carbamoyl]-2-methylpropyl}carbamoyl)-2-carboxyethyl]carbamoyl}butanoic acid

DATABASE IDS

MDL Number MFCD00236784
PubChem SID 24890940
CAS Number 144189-71-9

PROPERTIES

Purity ≥95% (HPLC)
Gene Information human ... APP(351)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met
Biochem/physiol Actions
Has cytotoxic effect on cultured neurons from rat hippocampus in serum free medium. Also forms aggregates and fibrils similar to those of β-amyloid protein in senile plaque cores.

REFERENCES