P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt

• Catalog No.: D1028
• CAS Number: 102783-33-5
• M. F.: C20H32N11O21P4+
• M. W.: 886.424224
• Purity: ~95% (HPLC)

SYNONYMS

• IUPAC name: ammonium {[5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[({[({[5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy})phosphinic acid
• IUPAC Traditional name: ammonium [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy[({[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy(hydroxy)phosphoryl]oxyphosphinic acid
• Synonyms: G(5′)P4(5′)G; Diguanosine tetraphosphate; GP4G

DATABASE IDS

• MDL Number: MFCD00058645
• CAS Number: 102783-33-5
• PubChem SID: 24893328

PROPERTIES

• Purity: ~95% (HPLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
P1,P4-Di(guanosine-5′) tetraphosphate (Diguanosine tetraphosphate) (GP4G) is a dinucleoside polyphosphate which may be used to study potential pathological effects of dinucleoside polyphosphtes in vivo. GP4G is an acceptor molecule for cytidine-3′, 5′-bisphosphate from the adenylylated donor 5′-adenylylated cytidine 5′,3′-bisphosphate in the T4 RNA ligase catalyzed reactions. GP4G is a used as an inhibitor of DNA apurinic/apyrimidinic endonuclease (APE1).