Amikacin disulfate salt

• Catalog No.: A1774
• CAS Number: 39831-55-5
• M. F.: C22H47N5O21S2
• M. W.: 781.75948

SYNONYMS

• IUPAC name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide; bis(sulfuric acid)
• IUPAC Traditional name: amikacin; bis(sulfuric acid)

DATABASE IDS

• EC Number: 254-648-6
• MDL Number: MFCD00167475
• Beilstein Number: 6172633
• PubChem SID: 24890586
• CAS Number: 39831-55-5

PROPERTIES

• Potency: 674-786 μg per mg (as amikacin base)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: WK1961200
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Application
Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria 1. It is used to study organism-directed delivery of antibiotics as well as drug resistance 2.
Biochem/physiol Actions
Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.