DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt hydrate

• Catalog No.: H6132
• CAS Number: 103476-21-7(anhydrous)
• M. F.: C27H48N7Na2O23P3S
• M. W.: 1009.668943
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: disodium trihydrate (2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3S)-3-{[2-({2-[(4-carboxy-3-hydroxy-3-methylbutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl phosphate
• IUPAC Traditional name: disodium trihydrate (2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-[({[(3S)-3-{[2-({2-[(4-carboxy-3-hydroxy-3-methylbutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropoxy(hydroxy)phosphoryl]oxy(hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl phosphate
• Synonyms: HMG-CoA

DATABASE IDS

• CAS Number: 103476-21-7(anhydrous)
• PubChem SID: 24895729

PROPERTIES

• Purity: ≥90% (HPLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is a substrate used to study the specificity and kinetics of the enzyme 3-hydroxyl-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase. HMG-CoA is the key intermediate in the biosynthsis of terpenes, cholesterol, and ketone bodies. Its metabolism is the target of statin drugs used to control cholesterol levels.