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Ampicillin sodium salt

Catalog No. A0166 Name Sigma Aldrich
CAS Number 69-52-3 Website http://www.sigmaaldrich.com
M. F. C16H18N3NaO4S Telephone 1-800-521-8956
M. W. 371.38659 Fax
Purity Email
Storage Chembase ID: 105415

SYNONYMS

Title
氨苄西林 钠盐
IUPAC name
sodium (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
IUPAC Traditional name
sodium ampicillin(1-)
Synonyms
氨苄青霉素 钠盐

DATABASE IDS

MDL Number MFCD00064313
PubChem SID 24890405
EC Number 200-708-1
Beilstein Number 4119211
CAS Number 69-52-3

PROPERTIES

Potency ≥845 μg per mg
Suitability suitable for cell culture
Apperance white with slight yellow cast powder
Melting Point 215 °C (dec.)(lit.)
Solubility H2O: soluble50 mg/mL (Stock solutions should be stored at -20 °C.)
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H317-H334
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P280-P342 + P311
Risk Statements 42/43
RTECS XH8400000
Safety Statements 22-36/37-45
Storage Temperature 2-8°C
German water hazard class 2

DETAILS

Description (简体中文)
Application
建议以 100mg/L 的抗菌用量用于细胞培养基中。 建议以 20-125μg/ml 的量用于氨苄西林抗性研究。 在 37°C 下可稳定 3 天。
Biochem/physiol Actions
β-内酰胺类抗生素,具有连接到青霉素结构上的氨基侧链。青霉素衍生物,通过灭活细菌细胞膜内表面上的转肽酶,抑制细菌细胞壁的合成(肽聚糖交联)。仅对生长的 Escherichia coli 具有杀菌作用。抗性方式:通过 β-内酰胺酶使氨苄西林的 β-内酰胺环分裂。抗菌谱:革兰氏阴性和革兰氏阳性细菌。
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

REFERENCES