(-)-Tetramisole hydrochloride

• Catalog No.: L9756
• CAS Number: 16595-80-5
• M. F.: C11H13ClN2S
• M. W.: 240.75232
• Purity: ≥99% (GC)

SYNONYMS

• Title: (-)-四咪唑/驱虫净 盐酸盐
• IUPAC name: (6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
• IUPAC Traditional name: levamisole hydrochloride hydrochloride
• Synonyms: L(-)-2,3,5,6-四氢-6-苯基咪唑并(2,1-b)噻唑 盐酸盐; (S)-(-)-6-苯基-2,3,5,6-四氢咪唑并[2,1-b]噻唑 盐酸盐; 左咪唑 盐酸盐

DATABASE IDS

• PubChem SID: 24278526
• MDL Number: MFCD00012675
• EC Number: 240-654-6
• CAS Number: 16595-80-5
• Beilstein Number: 4358988

PROPERTIES

• Risk Statements: 25
• RTECS: NJ5960000
• Safety Statements: 36/37/39-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Purity: ≥99% (GC)
• Melting Point: 228-230 °C

DETAILS

Description (简体中文)

Application
Suitable for inhibition of various mammalian alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited. Not for veterinary use.
Biochem/physiol Actions
Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors.1 Very effective in treatment of ascariasis (hookworm infestation).2 Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages.3
包装
5, 10 g in poly bottle
Other Notes
Levamisole hydrochloride is soluble in water at 50mg/mL yielding a clear, colorless solution. Solutions are stable at 2-8°C for ~1 month.