Cytochalasin B from Drechslera dematioidea

• Catalog No.: C6762
• CAS Number: 14930-96-2
• M. F.: C29H37NO5
• M. W.: 479.60778
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: 细胞松弛素 B 来源于Drechslera dematioidea
• IUPAC name: (5R,9R,13S,15S,15aS,16S,18aS,18bS)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,13H,14H,15H,15aH,16H,17H,18H,18bH-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
• IUPAC Traditional name: cytochalasin B
• Synonyms: Phomin

DATABASE IDS

• PubChem SID: 24892890
• CAS Number: 14930-96-2
• MDL Number: MFCD00077704
• Beilstein Number: 1096207
• EC Number: 239-000-2

PROPERTIES

• Purity: ≥98% (HPLC)
• Quality Level: PREMIUM
• Apperance: white powder
• Solubility: DMSO: soluble10 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H330-H361
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 1544 6.1/PG 2
• Risk Statements: 63-26/27/28
• RTECS: RO0205000
• Safety Statements: 28-36/37-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.