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Resiniferatoxin

Catalog No. R8756 Name Sigma Aldrich
CAS Number 57444-62-9 Website http://www.sigmaaldrich.com
M. F. C37H40O9 Telephone 1-800-521-8956
M. W. 628.7081 Fax
Purity ~95% Email
Storage Chembase ID: 133756

SYNONYMS

IUPAC name
[(1R,2R,6R,11R,13S,15R,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-yl]methyl 2-(3-hydroxy-5-methoxyphenyl)acetate
IUPAC Traditional name
[(1R,2R,6R,11R,13S,15R,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-yl]methyl 2-(3-hydroxy-5-methoxyphenyl)acetate

DATABASE IDS

MDL Number MFCD00135927
CAS Number 57444-62-9
Beilstein Number 5371150
PubChem SID 24899411

PROPERTIES

Biological Source from Euphorbia poisonii
Purity ~95%
Gene Information rat ... Trpv1(83810)
GHS Pictograms GHS05
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301-H314
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P280-P305 + P351 + P338-P310
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25-35
RTECS CY1633700
Safety Statements 26-36/37/39-45
Storage Temperature -20°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Potent VR1 vanilloid receptor agonist that has been used to label the vanilloid receptor in sensory ganglia; activates protein kinase C. Diterpene ester that is related to phorbol, but is not tumorigenic.

REFERENCES