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Ellagic acid

Catalog No. E2250 Name Sigma Aldrich
CAS Number 476-66-4 Website http://www.sigmaaldrich.com
M. F. C14H6O8 Telephone 1-800-521-8956
M. W. 302.19264 Fax
Purity ≥95% (HPLC) Email
Storage Chembase ID: 6080

SYNONYMS

Title
鞣花酸
IUPAC name
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione
IUPAC Traditional name
ellagic acid
Synonyms
4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone

DATABASE IDS

EC Number 207-508-3
CAS Number 476-66-4
PubChem SID 24894460
MDL Number MFCD00006914
Beilstein Number 47549

PROPERTIES

Biological Source from tree bark
Purity ≥95% (HPLC)
Gene Information human ... CSK(1445), DYRK1A(1859), GSK3B(2932), SRC(6714)rat ... Lyn(81515), Syk(25155)
Apperance powder
Solubility 1 M NaOH: soluble10 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS DJ2620000
Safety Statements 26-36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase.1 Used for the assay of factor XIIa in plasma.2 Contact activation in blood coagulation.3
A naturally occurring plant phenol that is a potent antioxidant presumably by acting as a scavenger of oxygen species produced by hydrogen peroxide treatment, and as a protector of the DNA double helix from alkylating agent injury. It therefore has anti-mutagenic and anti-carcinogenic properties. Also reported to inhibit topoisomerases I and II and gyrase.

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