Ellagic acid

• Catalog No.: E2250
• CAS Number: 476-66-4
• M. F.: C14H6O8
• M. W.: 302.19264
• Purity: ≥95% (HPLC)

SYNONYMS

• Title: 鞣花酸
• IUPAC name: 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^4,^1^6.0^1^1,^1^5]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione
• IUPAC Traditional name: ellagic acid
• Synonyms: 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone

DATABASE IDS

• EC Number: 207-508-3
• CAS Number: 476-66-4
• PubChem SID: 24894460
• MDL Number: MFCD00006914
• Beilstein Number: 47549

PROPERTIES

• Biological Source: from tree bark
• Purity: ≥95% (HPLC)
• Gene Information: human ... CSK(1445), DYRK1A(1859), GSK3B(2932), SRC(6714)rat ... Lyn(81515), Syk(25155)
• Apperance: powder
• Solubility: 1 M NaOH: soluble10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: DJ2620000
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase.1 Used for the assay of factor XIIa in plasma.2 Contact activation in blood coagulation.3
A naturally occurring plant phenol that is a potent antioxidant presumably by acting as a scavenger of oxygen species produced by hydrogen peroxide treatment, and as a protector of the DNA double helix from alkylating agent injury. It therefore has anti-mutagenic and anti-carcinogenic properties. Also reported to inhibit topoisomerases I and II and gyrase.