Dihydrostreptomycin sesquisulfate

• Catalog No.: D7253
• CAS Number: 5490-27-7
• M. F.: C42H88N14O36S3
• M. W.: 1461.41532
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: bis(1-[(1R,2S,3S,4R,5S,6S)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl]guanidine); tris(sulfuric acid)
• IUPAC Traditional name: bis(1-[(1R,2S,3S,4R,5S,6S)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl]guanidine); tris(sulfuric acid)

DATABASE IDS

• Beilstein Number: 3894221
• PubChem SID: 24894093
• EC Number: 226-823-7
• CAS Number: 5490-27-7
• MDL Number: MFCD00070252

PROPERTIES

• Purity: ≥98% (TLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Risk Statements: 22
• RTECS: WK2236000
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Mode of action: inhibits bacterial protein synthesis at the level of the 30S ribosomal subunit and the 16S rRNA.
Application
Dihydrostreptomycin sesquisulfate is an antibiotic used in aminoglycoside uptake studies1,2. It has also been used as an electrode for a cochlear amplifier in the hair-cell bundle of lizards3.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information