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Choline chloride_Molecular_structure_CAS_67-48-1)
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Choline chloride

Catalog No. C7527 Name Sigma Aldrich
CAS Number 67-48-1 Website http://www.sigmaaldrich.com
M. F. C5H14ClNO Telephone 1-800-521-8956
M. W. 139.62376 Fax
Purity ≥98% Email
Storage Chembase ID: 102374

SYNONYMS

Title
氯化胆碱
IUPAC name
(2-hydroxyethyl)trimethylazanium chloride
IUPAC Traditional name
choline chloride
Synonyms
(2-羟乙基)三甲基氯化铵

DATABASE IDS

CAS Number 67-48-1
Beilstein Number 3563126
PubChem SID 24892968
MDL Number MFCD00011721
EC Number 200-655-4

PROPERTIES

Purity ≥98%
Suitability suitable for cell culture
Suitability suitable for insect cell culture
Apperance powder
Melting Point 302-305 °C (dec.)(lit.)
Solubility H2O: soluble50 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS KH2975000
Safety Statements 26-36
German water hazard class 1

DETAILS

Description (简体中文)
Application
A source of methyl groups for methyl-transfer reactions.
Substrates
胆碱乙酰基转移酶底物
Biochem/physiol Actions
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1.

REFERENCES