Aphidicolin from Nigrospora sphaerica

• Catalog No.: A0781
• CAS Number: 38966-21-1
• M. F.: C20H34O4
• M. W.: 338.48156
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (1S,2S,5R,6R,7R,10S,12R,13R)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.0^1,^1^0.0^2,^7]hexadecane-5,13-diol
• IUPAC Traditional name: aphidicolin
• Synonyms: APC

DATABASE IDS

• Beilstein Number: 4689958
• MDL Number: MFCD00083214
• PubChem SID: 24890452
• CAS Number: 38966-21-1

PROPERTIES

• Purity: ≥98% (HPLC)
• Quality Level: PREMIUM
• Gene Information: human ... POLA1(5422), POLD1(5424), POLG(5428)
• Apperance: white powder
• Melting Point: 227-233 °C(lit.)
• Optical Rotation: [α]27/D +12°, c = 1 in methanol(lit.)
• Solubility: ethanol: soluble1 mg/mL (stable at least a week at 4°C.)
• Solubility: DMSO: soluble10 mg/mL (stable at least six weeks at -20°C.)
• Solubility: methanol: soluble10 mg/mL
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: PB9185000
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
Caution
Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.