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Ampicillin trihydrate_Molecular_structure_CAS_7177-48-2)
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Ampicillin trihydrate

Catalog No. A6140 Name Sigma Aldrich
CAS Number 7177-48-2 Website http://www.sigmaaldrich.com
M. F. C16H25N3O7S Telephone 1-800-521-8956
M. W. 403.4506 Fax
Purity 96.0-100.5% anhydrous basis (HPLC) Email
Storage Chembase ID: 105414


氨苄西林 三水合物
IUPAC name
(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
IUPAC Traditional name
ampicillin trihydrate


CAS Number 7177-48-2
Beilstein Number 5399534
MDL Number MFCD00072036
EC Number 200-709-7
PubChem SID 24891059


Purity 96.0-100.5% anhydrous basis (HPLC)
Melting Point 198-200 °C (dec.)(lit.)
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H315-H317-H319-H334-H335
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P280-P305 + P351 + P338-P342 + P311
Risk Statements 36/37/38-42/43
RTECS XH8425000
Safety Statements 22-26-36/37
Storage Temperature 2-8°C
German water hazard class 2


Description (English)
Biochem/physiol Actions
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells.