Ro 31-0432

• Catalog No.: R137
• CAS Number: 145333-02-4
• M. F.: C28H29ClN4O2
• M. W.: 489.00846
• Storage: protect from light

SYNONYMS

• IUPAC name: 3-{8-[(dimethylamino)methyl]-6H,7H,8H,9H-pyrido[1,2-a]indol-3-yl}-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride
• IUPAC Traditional name: 3-{8-[(dimethylamino)methyl]-6H,7H,8H,9H-pyrido[1,2-a]indol-3-yl}-4-(1-methylindol-3-yl)-1H-pyrrole-2,5-dione hydrochloride
• Synonyms: Bisindoylmaleimide XI; 3-(8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)-4-(1-methylindol-3-yl)maleimide hydrochloride; 3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione monohydrochloride

DATABASE IDS

• CAS Number: 145333-02-4

PROPERTIES

• Apperance: orange solid
• Solubility: DMSO: soluble5 mg/mL
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Condition: protect from light
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
GRK-5 (G protein-coupled receptor kinase) inhibitor; less potent inhibitor of GRK-2 or GRK-3; protein kinase C (PKC) inhibitor; membrane-derived PKC inhibitor.
Caution
Photosensitive