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N2,2′-O-Dibutyrylguanosine 3′,5′-cyclic monophosphate sodium salt hydrate_Molecular_structure_CAS_51116-00-8)
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N2,2′-O-Dibutyrylguanosine 3′,5′-cyclic monophosphate sodium salt hydrate

Catalog No. D3510 Name Sigma Aldrich
CAS Number 51116-00-8 Website http://www.sigmaaldrich.com
M. F. C18H24N5NaO9P Telephone 1-800-521-8956
M. W. 508.374791 Fax
Purity ≥95% (HPLC) Email
Storage Chembase ID: 133692

SYNONYMS

IUPAC name
6-(2-butanamido-6-oxo-6,9-dihydro-3H-purin-9-yl)-2-hydroxy-2-oxo-hexahydro-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-7-yl butanoate sodium
IUPAC Traditional name
6-(2-butanamido-6-oxo-3H-purin-9-yl)-2-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-7-yl butanoate sodium

DATABASE IDS

CAS Number 51116-00-8
MDL Number MFCD00038422
PubChem SID 24893759
EC Number 256-992-2

PROPERTIES

Purity ≥95% (HPLC)
Apperance off-white powder
Solubility H2O: soluble50 mg/mL
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Cell permeable, cGMP analog that activates protein kinase G. Has been shown to increase intracellular calcium concentration in neurons and hepatocytes. Inhibits thrombin-induced arachidonic acid release in platelets. Increases endothelial P-selectin expression via activation of protein kinase G. Used to study the activation of p38 mitogen-activated protein kinase by lipopolysaccharide in neutrophils.

REFERENCES