Efaroxan hydrochloride

• Catalog No.: E3263
• CAS Number: 89197-00-2
• M. F.: C13H17ClN2O
• M. W.: 252.73988
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(2-ethyl-2,3-dihydro-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
• IUPAC Traditional name: efaroxan hydrochloride
• Synonyms: 2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride; RX 821037A

DATABASE IDS

• PubChem SID: 24278415
• CAS Number: 89197-00-2
• MDL Number: MFCD00069270

PROPERTIES

• Purity: ≥98% (HPLC)
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
• Solubility: H2O: >20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 7-35-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
(+)-Isomer is a selective α-adrenoceptor antagonist; (-)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I1 imidazoline binding site antagonist.