Mecamylamine hydrochloride

• Catalog No.: M9020
• CAS Number: 826-39-1
• M. F.: C11H22ClN
• M. W.: 203.75208

SYNONYMS

• IUPAC name: (1S,4R)-N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride
• IUPAC Traditional name: (1S,4R)-N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride
• Synonyms: 2-(Methylamino)isocamphane hydrochloride; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride; Inversine

DATABASE IDS

• EC Number: 212-555-8
• CAS Number: 826-39-1
• PubChem SID: 24277851
• MDL Number: MFCD00151462

PROPERTIES

• Solubility: ethanol: soluble122 mg/mL
• Solubility: H2O: soluble47 mg/mL
• Solubility: isopropanol: soluble476 mg/mL
• Solubility: glycerol: soluble95 mg/mL
• Safety Statements: 36/37/39
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 22-36/37/38
• RTECS: RB6900000
• Gene Information: human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

DETAILS

Description (English)

Biochem/physiol Actions
Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
Caution
Solutions are stable to autoclaving.