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N-Acetyl-D-mannosamine

Catalog No. A8176 Name Sigma Aldrich
CAS Number 7772-94-3 Website http://www.sigmaaldrich.com
M. F. C8H15NO6 Telephone 1-800-521-8956
M. W. 221.2078 Fax
Purity ≥98% (TLC) Email
Storage Chembase ID: 133596

SYNONYMS

Title
N-乙酰-D-甘露糖胺
IUPAC name
N-[(2S,3S,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
IUPAC Traditional name
N-acetyl-α-D-mannosamine

DATABASE IDS

PubChem SID 24891208
CAS Number 7772-94-3

PROPERTIES

Purity ≥98% (TLC)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (简体中文)
Biochem/physiol Actions
N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of polysialic acid. Transport studies in the E. coli K1 strain have been performed to probe the effect of ManNAc on capsular polysialic acid production.
包装
10 mg in autosmp vl
Application
N-Acetyl-D-mannosamine (ManNAc) is used as a substrate to identify, differentiate and characterize enzymes such as N-acetyl-glucosamine epimerase(s) and aldolase(s). N-Acetyl-D-mannosamine is used for the synthesis of of N-acetylneuraminic acid.
Protocols & Applications
Sialic Acid Synthesis and Signaling Overview

REFERENCES