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Guanosine 3′,5′-cyclic monophosphate_Molecular_structure_CAS_7665-99-8)
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Guanosine 3′,5′-cyclic monophosphate

Catalog No. G7504 Name Sigma Aldrich
CAS Number 7665-99-8 Website http://www.sigmaaldrich.com
M. F. C10H12N5O7P Telephone 1-800-521-8956
M. W. 345.205341 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 133594


IUPAC name
IUPAC Traditional name
cyclic guanosine monophosphate
cyclic GMP


MDL Number MFCD00070129
EC Number 231-641-6
PubChem SID 24895309
CAS Number 7665-99-8


Purity ≥98% (HPLC)
Apperance white powder
Solubility 1% NaHCO3: soluble50 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 22-26-36
Storage Temperature -20°C
German water hazard class 3


Description (English)
Biochem/physiol Actions
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. G7504.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.