Chelerythrine chloride

• Catalog No.: C2932
• CAS Number: 3895-92-9
• M. F.: C21H18ClNO4
• M. W.: 383.82492
• Purity: ≥95% (TLC)

SYNONYMS

• IUPAC name: 17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^2,^1^0.0^4,^8.0^1^4,^1^9]henicosa-1(13),2,4(8),9,11,14(19),15,17,20-nonaen-21-ium chloride
• IUPAC Traditional name: 17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^2,^1^0.0^4,^8.0^1^4,^1^9]henicosa-1(13),2,4(8),9,11,14(19),15,17,20-nonaen-21-ium chloride
• Synonyms: 1,2-Dimethoxy-N-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride

DATABASE IDS

• CAS Number: 3895-92-9
• PubChem SID: 24278305
• EC Number: 223-444-9
• MDL Number: MFCD00060717

PROPERTIES

• Purity: ≥95% (TLC)
• Apperance: yellow to orange powder
• Solubility: DMSO: soluble2 mg/mL
• Solubility: H2O: soluble5 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H315-H319-H332-H335
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P261-P280-P305 + P351 + P338
• Risk Statements: 20/21/22-36/37/38
• RTECS: FL9200000
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Chelerythrine affects translocation of PKC from cytosol to plasma membrane. Shown to prevent neurite growth. Induces apoptosis in a concentration- and schedule-dependent manner.