Fumonisin B2 from Fusarium moniliforme

• Catalog No.: F3771
• CAS Number: 116355-84-1
• M. F.: C34H59NO14
• M. W.: 705.83056

SYNONYMS

• IUPAC name: 2-[2-({19-amino-6-[(3,4-dicarboxybutanoyl)oxy]-16,18-dihydroxy-5,9-dimethylicosan-7-yl}oxy)-2-oxoethyl]butanedioic acid
• IUPAC Traditional name: fumonisin B2

DATABASE IDS

• PubChem SID: 24894857
• MDL Number: MFCD00133350
• CAS Number: 116355-84-1

PROPERTIES

• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H315-H319-H330-H335-H351
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P302 + P350-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 1
• Risk Statements: 26/27/28-36/37/38-40
• RTECS: TZ8335000
• Safety Statements: 22-36/37/39-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.
General description
Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses.1 Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B2,2 so it is now a concern for human consumption of grapes, raisins, and wine.