Cephradine

• Catalog No.: C8395
• CAS Number: 38821-53-3
• M. F.: C16H19N3O4S
• M. W.: 349.40476

SYNONYMS

• IUPAC name: (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• IUPAC Traditional name: cefradine
• Synonyms: Cefradin

DATABASE IDS

• PubChem SID: 24278342
• CAS Number: 38821-53-3
• MDL Number: MFCD00865048

PROPERTIES

• GHS Signal Word: Danger
• GHS Hazard statements: H315-H317-H319-H334-H335
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P342 + P311
• Risk Statements: 36/37/38-42/43
• Safety Statements: 22-26-36/37-45
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Application
Cefradin is a semi-synthetic cephalosporin antibiotic that is used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Cefradin is used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cefradin may interfere with autolysin inhibitors.