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Canrenoic acid potassium salt_Molecular_structure_CAS_2181-04-6)
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Canrenoic acid potassium salt

Catalog No. C7287 Name Sigma Aldrich
CAS Number 2181-04-6 Website http://www.sigmaaldrich.com
M. F. C22H30KO4 Telephone 1-800-521-8956
M. W. 397.5695 Fax
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Storage Chembase ID: 133428


IUPAC name
3-[(1S,2R,10R,11S,14R,15S)-14-hydroxy-2,15-dimethyl-5-oxotetracyclo[,7.011,15]heptadeca-6,8-dien-14-yl]propanoic acid potassium
IUPAC Traditional name
canrenoic acid potassium
Potassium canrenoate
17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid


CAS Number 2181-04-6
MDL Number MFCD05662375
PubChem SID 24892953
EC Number 218-554-9


Apperance light yellow to tan powder
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Risk Statements 22
RTECS TU3500000
Safety Statements 36
German water hazard class 3


Description (English)
Aqueous solutions may contain some insoluble material.
Biochem/physiol Actions
Competitive aldosterone receptor antagonist. Potassium canrenoate reduces the effects of aldosterone-induced increases in blood pressure and in cardiovascular fibrosis in animals with high sodium intake. It is used clinically for its anti-fibrotic effects. At higher doses it is genotoxic to liver and increases tumor incidence in rodent models.