U-73122 hydrate

• Catalog No.: U6756
• CAS Number: 112648-68-7(anhydrous)
• M. F.: C29H42N2O4
• M. W.: 482.65478

SYNONYMS

• IUPAC name: 1-(6-{[(1S,10R,11S,14S,15S)-5-methoxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-14-yl]amino}hexyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrate
• IUPAC Traditional name: 1-(6-{[(1S,10R,11S,14S,15S)-5-methoxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-14-yl]amino}hexyl)pyrrole-2,5-dione hydrate
• Synonyms: 1-[6-[((17β)-3-Methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-1H-pyrrole-2,5-dione

DATABASE IDS

• PubChem SID: 24278065
• MDL Number: MFCD12910450
• CAS Number: 112648-68-7(anhydrous)

PROPERTIES

• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: room temp
• German water hazard class: 3
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• Apperance: off-white powder
• Solubility: ethanol: ~.7 mg/mL
• Solubility: DMSO: ~.9 mg/mL
• Solubility: chloroform: ~10 mg/mL
• Solubility: DMSO: ≤2.6 mg/mL (Achieved with heating.)
• Solubility: ethanol: ≤5 mg/mL (Achieved with heating.)
• Solubility: H2O: insoluble

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits the hydrolysis of PPI to IP3, which leads to a decrease in cytosolic free calcium. Inhibits the coupling of G protein-phospholipase C activation, while remaining unaffected by production of cAMP.