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Cefotaxime sodium salt_Molecular_structure_CAS_64485-93-4)
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Cefotaxime sodium salt

Catalog No. C7039 Name Sigma Aldrich
CAS Number 64485-93-4 Website http://www.sigmaaldrich.com
M. F. C16H16N5NaO7S2 Telephone 1-800-521-8956
M. W. 477.44731 Fax
Purity Email
Storage Chembase ID: 133418


Cefotaxime sodium salt 钠盐
IUPAC name
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
IUPAC Traditional name
sodium cefotaxime(1-)
Cefotaxim sodium salt 钠盐


CAS Number 64485-93-4
EC Number 264-915-9
MDL Number MFCD00079073
PubChem SID 24892923
Beilstein Number 5711411


Suitability plant cell culture tested
Apperance white to yellow powder
Solubility H2O: soluble (aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.)
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H317-H334
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P280-P342 + P311
Risk Statements 42/43
RTECS XI0250000
Safety Statements 22-36/37
Storage Temperature 2-8°C
German water hazard class 2


Description (English)
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information