Cefotaxime sodium salt

• Catalog No.: C7039
• CAS Number: 64485-93-4
• M. F.: C16H16N5NaO7S2
• M. W.: 477.44731

SYNONYMS

• Title: Cefotaxime sodium salt 钠盐
• IUPAC name: sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• IUPAC Traditional name: sodium cefotaxime(1-)
• Synonyms: Cefotaxim sodium salt 钠盐

DATABASE IDS

• CAS Number: 64485-93-4
• EC Number: 264-915-9
• MDL Number: MFCD00079073
• PubChem SID: 24892923
• Beilstein Number: 5711411

PROPERTIES

• Suitability: plant cell culture tested
• Apperance: white to yellow powder
• Solubility: H2O: soluble (aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.)
• GHS Signal Word: Danger
• GHS Hazard statements: H317-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P342 + P311
• Risk Statements: 42/43
• RTECS: XI0250000
• Safety Statements: 22-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information