Rhein

• Catalog No.: R7269
• CAS Number: 478-43-3
• M. F.: C15H8O6
• M. W.: 284.22042

SYNONYMS

• Title: 大黄酸
• IUPAC name: 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
• IUPAC Traditional name: rhein
• Synonyms: 1,8-二羟基-3-羧基蒽醌; 4,5-二羟基蒽醌-2-羧酸; 9,10-二氢-4,5-二羟基-9,10-二氧代-2-蒽羧酸

DATABASE IDS

• CAS Number: 478-43-3
• MDL Number: MFCD00009618
• EC Number: 207-521-4
• Beilstein Number: 2222155
• PubChem SID: 24899390

PROPERTIES

• Melting Point: ≥300 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: CA9516000
• Safety Statements: 26-37/39
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Constituent that is enriched in rhubarb with anti-inflammatory, anti-osteoarthritic, and anti-cancer activity. It reduces IL-1β production and secretion, caspase-3 activity, inducible nitric oxide synthase activity, and phosphorylation of c-Jun and c-Jun NH2-terminal kinase (JNK).